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1

Inflammatory Time Course after Quartz Instillation

Albrecht, Catrin, Schins, Roel P. F., Höhr, Doris, Becker, Andrea, Shi, Tingming, Knaapen, Ad M., Borm, Paul J. A.

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2004

File:

PDF, 209 KB

2004

2

Oxidative stress and calcium signaling in the adverse effects of environmental particles (PM10)

Ken Donaldson, Vicki Stone, Paul J.A. Borm, Luis A. Jimenez, Peter S. Gilmour, Roel P.F. Schins, Ad M. Knaapen, Irfan Rahman, Stephen P. Faux, David M. Brown, William MacNee

Journal:

Free Radical Biology and Medicine

Year:

2003

Language:

english

File:

PDF, 273 KB

english, 2003

3

Induction of CYP1A1 in rat lung cells following in vivo and in vitro exposure to quartz

Andrea Becker, Catrin Albrecht, Ad M. Knaapen, Roel P. F. Schins, Doris Höhr, Kirstin Ledermann, Paul J. A. Borm

Journal:

Archives of Toxicology

Year:

2006

Language:

english

File:

PDF, 501 KB

english, 2006

4

Transcriptional profiling of the acute pulmonary inflammatory response induced by LPS: role of neutrophils

Nejla Güngör, Jeroen LA Pennings, Ad M Knaapen, Roland K Chiu, Marco Peluso, Roger WL Godschalk, Frederik J Van Schooten

Journal:

Respiratory Research

Year:

2010

Language:

english

File:

PDF, 375 KB

english, 2010

5

Prevalence of at-risk genotypes for genotoxic effects decreases with age in a randomly selected population in Flanders: a cross sectional study

Hans B Ketelslegers, Roger WL Godschalk, Ralph WH Gottschalk, Ad M Knaapen, Gudrun Koppen, Greet Schoeters, Willy F Baeyens, Vera Nelen, Joep PM Geraedts, Joost HM van Delft, Jos CS Kleinjans, Nicolas

Journal:

Environmental Health

Year:

2011

Language:

english

File:

PDF, 304 KB

english, 2011

6

Extrapolation of toxic concentrations in in vitro assays by a high throughput PBPK model

Sieto Bosgra, Joost Westerhout, Ad Knaapen, Miriam Verwei

Journal:

Toxicology Letters

Year:

2012

Language:

english

File:

PDF, 85 KB

english, 2012

7

An inactivated poliovirus vaccine using Sabin strains produced on the serum-free PER.C6® cell culture platform is immunogenic and safe in a non-human primate model

Bockstal, Viki, Tiemessen, Machteld M., Achterberg, Rogier, Van Wordragen, Carlo, Knaapen, Ad M., Serroyen, Jan, Marissen, Wilfred E., Schuitemaker, Hanneke, Zahn, Roland

Journal:

Year:

2018

Language:

english

File:

PDF, 739 KB

english, 2018

8

Soluble metals as well as the insoluble particle fraction are involved in cellular DNA damage induced by particulate matter

Ad M. Knaapen, Tingming Shi, Paul J.A. Borm, Roel P.F. Schins

Journal:

Molecular and Cellular Biochemistry

Year:

2002

Language:

english

File:

PDF, 151 KB

english, 2002

9

DNA damage, mutagenesis and cardiovascular disease

Frederik J. van Schooten, Ad M. Knaapen, Alberto Izzotti

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2007

Language:

english

File:

PDF, 94 KB

english, 2007

10

Diesel Engine Exhaust Initiates a Sequence of Pulmonary and Cardiovascular Effects in Rats

Kooter, Ingeborg M., Gerlofs-Nijland, Miriam E., Boere, A. John F., Leseman, Daan L. A. C., Fokkens, Paul H. B., Spronk, Henri M. H., Frederix, Kim, ten Cate, Hugo, Knaapen, Ad M., Vreman, Hendrik J.,

Journal:

Journal of Toxicology

Year:

2010

Language:

english

File:

PDF, 1.24 MB

english, 2010

11

The environmental carcinogen benzo[a]pyrene induces expression of monocyte-chemoattractant protein-1 in vascular tissue: a possible role in atherogenesis

Ad M. Knaapen, Daniëlle M. Curfs, Daniëlle M. Pachen, Ralph W. Gottschalk, Menno P.J. de Winther, Mat J. Daemen, Frederik J. Van Schooten

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2007

Language:

english

File:

PDF, 434 KB

english, 2007

12

Surface Modification of Quartz Inhibits Toxicity, Particle Uptake, and Oxidative DNA Damage in Human Lung Epithelial Cells

Schins, Roel P. F., Duffin, Rodger, Höhr, Doris, Knaapen, Ad M., Shi, Tingming, Weishaupt, Christel, Stone, Vicki, Donaldson, Ken, Borm, Paul J. A.

Journal:

Chemical Research in Toxicology

Year:

2002

Language:

english

File:

PDF, 167 KB

english, 2002

13

Comparative evaluation of the effects of short-term inhalation exposure to diesel engine exhaust on rat lung and brain

Damien van Berlo, Catrin Albrecht, Ad M. Knaapen, Flemming R. Cassee, Miriam E. Gerlofs-Nijland, Ingeborg M. Kooter, Nicola Palomero-Gallagher, Hans-Jürgen Bidmon, Frederik-Jan van Schooten, Jean Krut

Journal:

Archives of Toxicology

Year:

2010

Language:

english

File:

PDF, 585 KB

english, 2010

14

Neutrophils and respiratory tract genotoxicity

Ad Knaapen, Nejla Güngör, Roger Godschalk, Roel Schins, Paul Borm, Frederik-Jan van Schooten

Journal:

Toxicology Letters

Year:

2007

Language:

english

File:

PDF, 78 KB

english, 2007

15

Mechanisms of neutrophil-induced DNA damage in respiratory tract epithelial cells

Ad M. Knaapen, Roel P.F. Schins, Dünya Polat, Andrea Becker, Paul J.A. Borm

Journal:

Molecular and Cellular Biochemistry

Year:

2002

Language:

english

File:

PDF, 132 KB

english, 2002

16

Formation of lysine 63-linked poly-ubiquitin chains protects human lung cells against benzo[a]pyrene-diol-epoxide-induced mutagenicity

Sabine A.S. Langie, Ad M. Knaapen, Chantal H.M.A. Ramaekers, Jan Theys, Jan Brun, Roger W.L. Godschalk, Frederik J. van Schooten, Philippe Lambin, Douglas A. Gray, Bradly G. Wouters, Roland K. Chiu

Journal:

Year:

2007

Language:

english

File:

PDF, 532 KB

english, 2007

17

Oxidant-induced DNA damage by quartz in alveolar epithelial cells

Roel P.F. Schins, Ad M. Knaapen, Gonca D. Cakmak, Tingming Shi, Christel Weishaupt, Paul J.A. Borm

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Year:

2002

Language:

english

File:

PDF, 196 KB

english, 2002

18

Ambient Particulate Matter Induces Oxidative Dna Damage in Lung Epithelial Cells

Knaapen, Ad M., Schins, Roel P.F., Steinfartz, Yvonne, Doris, Höhr, Dunemann, Lothar, Borm, Paul J.A.

Journal:

Inhalation Toxicology

Year:

2000

Language:

english

File:

PDF, 2.91 MB

english, 2000

19

Inhaled particles and lung cancer. Part A: Mechanisms

Ad M. Knaapen, Paul J.A. Borm, Catrin Albrecht, Roel P.F. Schins

Journal:

International Journal of Cancer

Year:

2004

Language:

english

File:

PDF, 287 KB

english, 2004

20

Genotoxicity of Poorly Soluble Particles

Schins, Roel P. F., Knaapen, Ad M.

Journal:

Inhalation Toxicology

Year:

2007

Language:

english

File:

PDF, 196 KB

english, 2007

21

Implications of gene–drug interactions in smoking cessation for improving the prevention of chronic degenerative diseases

Marieke Quaak, Constant P. van Schayck, Ad M. Knaapen, Frederik J. van Schooten

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2009

Language:

english

File:

PDF, 1.86 MB

english, 2009

22

Curcumin protects against cytotoxic and inflammatory effects of quartz particles but causes oxidative DNA damage in a rat lung epithelial cell line

Hui Li, Damien van Berlo, Tingming Shi, Günter Speit, Ad M. Knaapen, Paul J.A. Borm, Catrin Albrecht, Roel P.F. Schins

Journal:

Toxicology and Applied Pharmacology

Year:

2008

Language:

english

File:

PDF, 785 KB

english, 2008

23

Neutrophils cause oxidative DNA damage in alveolar epithelial cells

Ad M Knaapen, Frank Seiler, Pauline A.E.L Schilderman, Peter Nehls, Joachim Bruch, Roel P.F Schins, Paul J.A Borm

Journal:

Free Radical Biology and Medicine

Year:

1999

Language:

english

File:

PDF, 431 KB

english, 1999

24

β-Carotene metabolites enhance inflammation-induced oxidative DNA damage in lung epithelial cells

Yvonne G.J. van Helden, Jaap Keijer, Ad M. Knaapen, Sandra G. Heil, Jacob J. Briedé, Frederik J. van Schooten, Roger W.L. Godschalk

Journal:

Free Radical Biology and Medicine

Year:

2009

Language:

english

File:

PDF, 509 KB

english, 2009

25

Nanoparticle-induced inflammation and its effect on the base excision repair pathway in rat lungs

Anton Wessels, Catrin Albrecht, Ad Knaapen, Rodger Duffin, Damien van Berlo, Peter Voss, Klaus Unfried, Roel Schins

Journal:

Toxicology Letters

Year:

2007

Language:

english

File:

PDF, 80 KB

english, 2007

26

NF-κB dependent and independent mechanisms of quartz-induced proinflammatory activation of lung epithelial cells

Damien van Berlo, Ad M Knaapen, Frederik-Jan van Schooten, Roel PF Schins, Catrin Albrecht

Journal:

Particle and Fibre Toxicology

Year:

2010

Language:

english

File:

PDF, 1.52 MB

english, 2010

27

Investigations on the effects of short term diesel exhaust inhalation in rat brain

Damien van Berlo, Catrin Albrecht, Ad Knaapen, Flemming Cassee, Mirjam Gerlofs-Nijland, Ingeborg Kooter, Nicola Palomero-Gallagher, Hans Bidmon, Frederik-Jan van Schooten, Anton Wessels, Jean Krutmann

Journal:

Toxicology Letters

Year:

2007

Language:

english

File:

PDF, 85 KB

english, 2007

28

Hydroxyl radical generation by electron paramagnetic resonance as a new method to monitor ambient particulate matter composition

Shi, Tingming, Schins, Roel P. F., Knaapen, Ad M., Kuhlbusch, Thomas, Pitz, Mike, Heinrich, Joachim, Borm, Paul J. A.

Journal:

Journal of Environmental Monitoring

Year:

2003

Language:

english

File:

PDF, 174 KB

english, 2003

29

Supplement 5: Particle Toxicity || Neutrophils Amplify the Formation of DNA Adducts by Benzo[a]pyrene in Lung Target Cells

Paul J. A. Borm, Ad M. Knaapen, Roel P. F. Schins, Roger W. L. Godschalk and Frederik-Jan Van Schooten

Journal:

Environmental Health Perspectives

Year:

1997

Language:

english

File:

PDF, 454 KB

english, 1997

30

The surface area rather than the surface coating determines the acute inflammatory response after instillation of fine and ultrafine TiO2 in the rat

Doris Höhr, Yvonne Steinfartz, Roel P.F. Schins, Ad M. Knaapen, Gianmario Martra, Bice Fubini, Paul J.A. Borm

Journal:

International Journal of Hygiene and Environmental Health

Year:

2002

Language:

english

File:

PDF, 213 KB

english, 2002

31

A new type of sea bed waves

Knaapen, Michiel A. F., Hulscher, Suzanne J. M. H., de Vriend, Huib J., Stolk, Ad

Journal:

Geophysical Research Letters

Year:

2001

Language:

english

File:

PDF, 520 KB

english, 2001

32

Inhibition of the mitochondrial respiratory chain function abrogates quartz induced DNA damage in lung epithelial cells

Hui Li, Petra Haberzettl, Catrin Albrecht, Doris Höhr, Ad M. Knaapen, Paul J.A. Borm, Roel P.F. Schins

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2007

Language:

english

File:

PDF, 855 KB

english, 2007

33

Inflammatory Time Course after Quartz Instillation

Albrecht, Catrin, Schins, Roel P. F., Höhr, Doris, Becker, Andrea, Shi, Tingming, Knaapen, Ad M., Borm, Paul J. A.

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2004

Language:

english

File:

PDF, 209 KB

english, 2004

34

The role of glutathione in the regulation of nucleotide excision repair during oxidative stress

Sabine A.S. Langie, Ad M. Knaapen, Joyce M.J. Houben, Frederik C. van Kempen, Joep P.J. de Hoon, Ralph W.H. Gottschalk, Roger W.L. Godschalk, Frederik J. van Schooten

Journal:

Toxicology Letters

Year:

2007

Language:

english

File:

PDF, 212 KB

english, 2007

35

The crucial role of particle surface reactivity in respirable quartz-induced reactive oxygen/nitrogen species formation and APE/Ref-1 induction in rat lung

Catrin Albrecht, Ad M Knaapen, Andrea Becker, Doris Höhr, Petra Haberzettl, Frederik J van Schooten, Paul JA Borm, Roel PF Schins

Journal:

Respiratory Research

Year:

2005

Language:

english

File:

PDF, 1.74 MB

english, 2005

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